Therapeutic Actions
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Treats multiple aspects of cardiovascular
disease including atherosclerosis, improved
blood flow, LDL oxidation, and high blood
pressure
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High antioxidant activity (ORAC value=3186)
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Laboratory research suggests pomegranate may
be effective for cancer prevention,
diabetes, neurological health,
osteoarthritis, womens health, and has
anti-infective properties and blood pressure
lowering effects
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Pomexcellent is an extract designed to have
the same levels of punicosides, polyphenols,
and ellagic acid as pomegranate juice
Chinese Therapeutic Effects
Cooling, treats cough, throat
inflammation
Parasitic infections
Administration
1 to 2 tablets per day between meals;
one tablet per day (200mg) is the equivalent to
8-8.5oz of juice used in human studies. Some
trials suggest that the equivalent of 2 tablets
per week may be taken as a preventive dosage.
Ingredients
Pomegranate fruit extract standardized
to 40% punicosides
Formula Rationale
Pomegranate (Punica granatum) originated
in North Africa and the Middle East and is now
found throughout the world. In the eighteenth
century, it was brought to California by the
Spanish. Pomegranate juice is a rich source of
polyphenols, tannins, and anthocyanins (OPC). It
has antioxidant and antiatherosclerotic
properties. Animal studies have shown that
polyphenolic antioxidants inhibit the oxidation
of LDL cholesterol, and reduce atherosclerosis,
the accumulation of plaque on arterial walls,
which can increase the risk of cardiovascular
problems such as heart attack and stroke. It has
been suggested that pomegranates combat
atherosclerosis by stimulating the enzyme
activity of paraoxonase (PON) and HDL-associated
protein. Pomegranate increases PON activity in
patients with high cholesterol and diabetes.
In a study of forty-five patients between the
ages of fifty-nine to seventy-nine with stable
coronary heart disease (CHD), subjects were
confirmed to have stress induced ischemia
evidenced by at least one myocardial perfusion.
The patients were assigned to randomly receive
8oz (240ml) of pomegranate juice or a sports
beverage similar to pomegranate juice.
Episodes of angina decreased by 50 percent in
the pomegranate group, but increased by 38
percent in the placebo group. Although there
were no significant changes in blood pressure,
lipids, glucose or Alc, the average myocardial
perfusion improvement was 17 percent in the
pomegranate group and a worsening of 18 percent
in placebo group (a 35 percent difference
between the 2 groups). Principle investigator
Dean Ornish, MD, stated, "Although the sample in
this study was relatively small, the strength of
the design and the significant improvements in
blood flow to the heart observed after only
three months suggest that pomegranate juice may
have important clinical benefits in those with
coronary heart disease".
Additional studies have focused on preventing
and treating atherosclerosis, diabetes,
neurological health, osteoarthritis,
antibacterial effects, chronic obstructive
pulmonary disease (COPD) and as a cancer
prevention herb. Pomegranate has been
traditionally used to treat infections,
diarrhea, and to reduce fever.
Health Concerns's Pomexcellent" is assayed to
contain 40 percent punicosides, the same as
fresh pomegranate juice. The advantage of
Pomexcellent is that it is standardized to water
soluble punicosides and not ellagic acid.
Pomexcellent pomegranate extract provides its
antioxidant benefits via an array of polyphenols
present in the fruit's seeds, husk and juice,
and is particularly rich in punicalagins.
Pomexcellent has a superior punicalagin profile
as well as a higher phenolic content than
typical juices or ready-made products, without
the sugar, carbohydrates, calories or allergens.
With an ORAC (Oxygen Radical Absorbance
Capacity) value of over 3,000 Pomexcellent is
one of nature's premier antioxidants.
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